Found 162 matching trials
The Effects of Human Endotoxemia on Functional Capacity of Hematopoietic Stem and Progenitor Cells NA We will investigate whether human endotoxemia induces changes in human bone...
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Intensive Care Medicine, Radboud University Nijmegen Medical Centre
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Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of BI 653048 BS H3PO4 Capsule Assessing Endotoxin-induced Inflammatory Response in Healthy Male Subjects PHASE1 The general aim of the current study was to investigate the safety and tole...
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Multiple Locations
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Immunomodulatory Effects of Dexamethasone, Tocilizumab and Anakinra During Experimental Human Endotoxemia PHASE4 The goal of this clinical trial is to investigate the immunomodulatory effe...
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Intensive Care Medicine, Radboud University Nijmegen Medical Centre
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Short-Chain Fatty Acids in Lypopolysaccharide-Induced Inflammation and Executive Function NA Short-chain fatty acids (SCFAs) are substances produced by gut bacteria whe...
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University Hospital Leuven (UZ Leuven)
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PET Imaging of Endotoxin-induced iNOS Activation PHASE1 The overall purpose of this research is to gain understanding of the basic ...
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Washington University School of Medicne
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Study of Biomarkers of Airway Inflammation (0000-128) PHASE1 This study will evaluate the effects of inhaled fluticasone on cell counts ...
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Multiple Locations
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Neutrophil Imaging in Healthy Subjects Following Lipopolysaccharide or Saline Challenge and in Subjects With Chronic Obstructive Pulmonary Disease PHASE1 This is an exploratory study to further develop an imaging platform for the...
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GSK Investigational Site
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Bacterial Translocation Markers as Predictors of Infectious and Inflammatory Complications in Acute Bowel Obstruction N/A Despite modern approaches to the diagnosis and treatment of acute bowel obs...
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NJSC Karaganda Medical University
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Early Prediction of Sepsis by Using Metabolomics N/A Sepsis is a serious medical condition associated with a high incidence and ...
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Southwest Hospital
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Nasal Inflammation Following Endotoxin Challenge in Patients With Asthma PHASE1 A phase I clinical research study aimed at determining mechanisms that regu...
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National Jewish Health
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